Wisconsin microbiome study, a cross-sectional investigation of dietary fiber, microbiome composition and antibiotic-resistant organisms

Shoshannah Eggers et al.

This study collected and analyzed biological specimens to explore the relationship between dietary fiber intake, gut microbiota composition, and multidrug-resistant organism (MDRO) colonization.

The project involved collecting biospecimens from 600 Wisconsin residents, including nasal, oral, and skin swabs, saliva, and stool. These samples were analyzed for MDRO presence and used for DNA extraction and 16S ribosomal RNA-based microbiota sequencing. The study also assessed associations between dietary fiber consumption, gut microbiota composition, and MDRO colonization.

Data and biospecimen from this study, Winning the War on Antibiotic Resistance (WARRIOR), are available for research purposes through the REACH program.

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